Modern Internet Technologies for Hypermedia Information Systems Describing Ensembles of Genes-Controllers of Development.

Alexander V. Spirov: Modern Internet Technologies for Hypermedia Information Systems Describing Ensembles of Genes-Controllers of Development CSIT 1999 : E/E

Abstract

Nowadays homeobox genes were found for species of main invertebrate and vertebrate phyla. It is established that these genes play key role in time and space orchestration of genome expression during development. Auto- and crossregulatory functional interactions join homeobox genes into genetic networks. For the purpose to orange all available data on structure, functions, phylogeny and evolution of Hox-genes, HOX-clusters and Hox-networks we develop specialized database HOX-Pro. Its main location is http://www.iephb.ru/~spirov/hox_pro/hox-pro00.html. The DB is also mirrored at http://www.mssm.edu/molbio/hoxpro/new/hox-pro00.html. The distinctive feature of the HOX Pro is its ability to serve not only as an information resource but also as tool for derivation of new knowledge by means of computational analysis. The long-range goal of HOX Pro is the functional reconstruction and prediction of genetic regulatory pathways from genomic sequence information.

Copyright © 1999 by the Institute for Contemporary Education "JurInfoR-MSU". Permission to copy without fee all or part of this material is granted provided that the copies are not made or distributed for direct commercial advantage, the CSIT copyright notice and the title of the publication and its date appear, and notice is given that copying is by permission of the Institute for Contemporary Education JMSUICE. To copy otherwise, or to republish, requires a fee and/or special permission from the JMSUICE.

Printed Edition

Ch. Freytag and V. Wolfengagen (Eds.): CSIT'99, Proceedings of 1st International Workshop on Computer Science and Information Technologies, January 18-22, 1999, Moscow, Russia. MEPhI Publishing 1999, ISBN 5-7262-0263-5

Electronic Edition